Biotinylated SARS-CoV-2 Spike S2 Domain

• Description:

  Biotinylated SARS-CoV-2 Spike S2 Domain _x000D_ Catalog number: B2010510_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 25 ug_x000D_ Molecular Weight or Concentration: 56 kDa_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: molecular component of many serological and antigenic assays for SARS-CoV-2_x000D_ Storage: -20„ƒ_x000D_ Keywords: Spike S2, S2 protein, Biotin S2_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ Download SARS-CoV-2 Brochure_x000D_ _x000D_ References:_x000D_ 1: Ho M. Perspectives on the development of neutralizing antibodies against_x000D_ SARS-CoV-2. Antib Ther. 2020 Apr;3(2):109-114._x000D_ _x000D_ 2: Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Manne K, Stalls V,_x000D_ Kopp MF, Henderson R, Edwards RJ, Haynes BF, Acharya P. D614G Mutation Alters_x000D_ SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2_x000D_ Junction. Cell Rep. 2021 Jan 12;34(2):108630._x000D_ _x000D_ 3: Ravichandran S, Coyle EM, Klenow L, Tang J, Grubbs G, Liu S, Wang T, Golding_x000D_ H, Khurana S. Antibody signature induced by SARS-CoV-2 spike protein immunogens_x000D_ in rabbits. Sci Transl Med. 2020 Jul 1;12(550):eabc3539._x000D_ _x000D_ 4: Zheng Z, Monteil VM, Maurer-Stroh S, Yew CW, Leong C, Mohd-Ismail NK,_x000D_ Cheyyatraivendran Arularasu S, Chow VTK, Lin RTP, Mirazimi A, Hong W, Tan YJ._x000D_ Monoclonal antibodies for the S2 subunit of spike of SARS-CoV-1 cross-react with_x000D_ the newly-emerged SARS-CoV-2. Euro Surveill. 2020 Jul;25(28):2000291._x000D_ _x000D_ 5: Pace RM, Williams JE, Järvinen KM, Belfort MB, Pace CD, Lackey KA, Gogel AC,_x000D_ Nguyen-Contant P, Kanagaiah P, Fitzgerald T, Ferri R, Young B, Rosen-Carole C,_x000D_ Diaz N, Meehan C, Caffe B, Sangster MY, Topham DJ, McGuire MA, Seppo A, McGuire_x000D_ MK. COVID-19 and human milk: SARS-CoV-2, antibodies, and neutralizing capacity._x000D_ medRxiv [Preprint]. 2020 Sep 18:2020.09.16.20196071._x000D_ _x000D_ 6: Nguyen-Contant P, Embong AK, Kanagaiah P, Chaves FA, Yang H, Branche AR,_x000D_ Topham DJ, Sangster MY. S Protein-Reactive IgG and Memory B Cell Production_x000D_ after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit._x000D_ mBio. 2020 Sep 25;11(5):e01991-20._x000D_ _x000D_ 7: Secchi M, Bazzigaluppi E, Brigatti C, Marzinotto I, Tresoldi C, Rovere-_x000D_ Querini P, Poli A, Castagna A, Scarlatti G, Zangrillo A, Ciceri F, Piemonti L,_x000D_ Lampasona V. COVID-19 survival associates with the immunoglobulin response to_x000D_ the SARS-CoV-2 spike receptor binding domain. J Clin Invest. 2020 Dec_x000D_ 1;130(12):6366-6378._x000D_ _x000D_ 8: Vilcek S. SARS-CoV-2: Zoonotic origin of pandemic coronavirus. Acta Virol._x000D_ 2020;64(3):281-287._x000D_ _x000D_ 9: Gobeil S, Janowska K, McDowell S, Mansouri K, Parks R, Manne K, Stalls V,_x000D_ Kopp M, Henderson R, Edwards RJ, Haynes BF, Acharya P. D614G mutation alters_x000D_ SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at_x000D_ the S1/S2 junction. bioRxiv [Preprint]. 2020 Oct 12:2020.10.11.335299._x000D_ 10: Satarker S, Nampoothiri M. Structural Proteins in Severe Acute Respiratory_x000D_ Syndrome Coronavirus-2. Arch Med Res. 2020 Aug;51(6):482-491. _x000D_ _x000D_ Products Related to Biotinylated SARS-CoV-2 Spike S2 Domain : SARS-CoV-2

• Short Description:

  Catalog Number: B2010510 (25 ug)_x000D_ Biotinylated SARS-CoV-2 Spike S2 Domain is a highly pure biotinylated recombinant SARS-CoV-2 S2 domain from the origical wild type lineage expressed in insect cells. This product has been used as molecular component of many serological and antigenic assays for SARS-CoV-2. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5