Biotinylated SARS-CoV-2 Spike S1 Domain

• Description:

  Biotinylated SARS-CoV-2 Spike S1 Domain _x000D_ Catalog number: B2010508_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 25 ug_x000D_ Molecular Weight or Concentration: 76 kDa_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: molecular component of many serological and antigenic assays for SARS-CoV-2_x000D_ Storage: -20„ƒ_x000D_ Keywords: Spike S1, S1 protein, Biotin S1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ Download SARS-CoV-2 Brochure_x000D_ _x000D_ References:_x000D_ 1: Kadam SB, Sukhramani GS, Bishnoi P, Pable AA, Barvkar VT. SARS-CoV-2, the_x000D_ pandemic coronavirus: Molecular and structural insights. J Basic Microbiol. 2021_x000D_ Mar;61(3):180-202._x000D_ _x000D_ 2: Kemp SA, Collier DA, Datir R, Ferreira I, Gayed S, Jahun A, Hosmillo M, Rees-_x000D_ Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N; CITIID-NIHR_x000D_ BioResource COVID-19 Collaboration; COVID-19 Genomics UK (COG-UK) Consortium,_x000D_ Sharrocks K, Blane E, Briggs J, van GM, Smith K, Bradley JR, Smith C, Doffinger_x000D_ R, Ceron-Gutierrez L, Barcenas-Morales G, Pollock DD, Goldstein RA, Smielewska_x000D_ A, Skittrall JP, Gouliouris T, Goodfellow IG, Gkrania-Klotsas E, Illingworth C,_x000D_ McCoy LE, Gupta RK. Neutralising antibodies in Spike mediated SARS-CoV-2_x000D_ adaptation. medRxiv [Preprint]. 2020 Dec 29:2020.12.05.20241927._x000D_ _x000D_ 3: Shajahan A, Supekar NT, Gleinich AS, Azadi P. Deducing the N- and_x000D_ O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2._x000D_ Glycobiology. 2020 Dec 9;30(12):981-988._x000D_ _x000D_ 4: Zhang L, Jackson CB, Mou H, Ojha A, Peng H, Quinlan BD, Rangarajan ES, Pan A,_x000D_ Vanderheiden A, Suthar MS, Li W, Izard T, Rader C, Farzan M, Choe H. SARS-CoV-2_x000D_ spike-protein D614G mutation increases virion spike density and infectivity. Nat_x000D_ Commun. 2020 Nov 26;11(1):6013._x000D_ _x000D_ 5: Zhou H, Chen X, Hu T, Li J, Song H, Liu Y, Wang P, Liu D, Yang J, Holmes EC,_x000D_ Hughes AC, Bi Y, Shi W. A Novel Bat Coronavirus Closely Related to SARS-CoV-2_x000D_ Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein._x000D_ Curr Biol. 2020 Jun 8;30(11):2196-2203.e3. doi: 10.1016/j.cub.2020.05.023. Epub_x000D_ 2020 May 11. Erratum in: Curr Biol. 2020 Oct 5;30(19):3896._x000D_ _x000D_ 6: Huang Y, Yang C, Xu XF, Xu W, Liu SW. Structural and functional properties of_x000D_ SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19._x000D_ Acta Pharmacol Sin. 2020 Sep;41(9):1141-1149._x000D_ _x000D_ 7: Kaur G, Lungarella G, Rahman I. SARS-CoV-2 COVID-19 susceptibility and lung_x000D_ inflammatory storm by smoking and vaping. J Inflamm (Lond). 2020 Jun 10;17:21._x000D_ _x000D_ 8: Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres_x000D_ JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR 3rd,_x000D_ Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB. Structural analysis of full-_x000D_ length SARS-CoV-2 spike protein from an advanced vaccine candidate. Science._x000D_ 2020 Nov 27;370(6520):1089-1094._x000D_ _x000D_ 9: Wang Y, Wang L, Cao H, Liu C. SARS-CoV-2 S1 is superior to the RBD as a_x000D_ COVID-19 subunit vaccine antigen. J Med Virol. 2021 Feb;93(2):892-898._x000D_ 10: Ho M. Perspectives on the development of neutralizing antibodies against_x000D_ SARS-CoV-2. Antib Ther. 2020 Apr;3(2):109-114. _x000D_ _x000D_ Products Related to Biotinylated SARS-CoV-2 Spike S1 Domain : SARS-CoV-2

• Short Description:

  Catalog Number: B2010508 (25 ug)_x000D_ Biotinylated SARS-CoV-2 Spike S1 Domain is a highly pure biotinylated recombinant SARS-CoV-2 S1 domain from the origical wild type lineage expressed in insect cells. This product has been used as molecular component of many serological and antigenic assays for SARS-CoV-2. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5