MMP14 Antibody

CAT: 0800-R31696Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R31696Size:100 µg
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Description
Matrix metalloproteinase-14, also called MT1-MMP, is an enzyme that in humans is encoded by the MMP14 gene. The protein encoded by this gene is a member of the membrane-type MMP subfamily. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene may be involved in actin cytoskeleton reorganization by cleaving PTK7. It acts as a positive regulator of cell growth and migration via activation of MMP15.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human MMP14 (LAVFFFRRHGTPRRLLYCQRSLLDKV) was used as the immunogen for this MMP14 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the MMP14 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MMP14 antibody is available for research use only.
Storage Conditions
After reconstitution, the MMP14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the MMP14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of MMP14 antibody and Lane 1: human placenta; 2: HeLa; 3: U87 lysate. Predicted molecular weight: ~66/54kDa.

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