Products for Research Use Only
RegisterLogin

MMP11 Antibody

CAT: 0800-R32703Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R32703Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Stromelysin-3 (SL-3) also known as matrix metalloproteinase-11 (MMP-11) is an enzyme that in humans is encoded by the MMP11 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 1-2 µg/mL
UniProt
P24347
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 104-135 (RWEKTDLTYRILRFPWQLVQEQVRQTMAEALK) from the human protein were used as the immunogen for the MMP11 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
Reconstitution
After reconstitution, the MMP11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MMP11 antibody is available for research use only.
Storage Conditions
After reconstitution, the MMP11 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the MMP11 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) rat spleen and 2) human MM231 lysate with MMP11 antibody at 0.5ug/ml. Predicted molecular weight ~55 kDa.
Product Datasheet
Loading...

Related Products

CatalogName
R30451MMP10 Antibody
R35709-100UGMMP12 Antibody
R30291MMP16 Antibody
F40218-0.08MLMMP14 Antibody
F54299-0.4MLMMP12 Antibody
F54844-0.4MLMMP14 Antibody
R32966MMP16 Antibody
R31696MMP14 Antibody
F54844-0.08MLMMP14 Antibody
F40218-0.4MLMMP14 Antibody

Alternative Products

CatalogName
GTR18133156MMP11 Antibody

Popular Products