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MMP10 Antibody

CAT: 0800-R30451Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30451Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Stromelysin-2 also known as matrix metalloproteinase-10 or transin-2 is an enzyme that in humans is encoded by the MMP10 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P09238
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human MMP10 (FDENSQSMEQGFP) was used as the immunogen for this MMP10 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the MMP10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MMP10 antibody is available for research use only.
Storage Conditions
After reconstitution, the MMP10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the MMP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Secreted
Image Legend
Western blot testing of MMP10 antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3: 2.5ng; 4: HeLa lysate.

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