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MAC-1 Antibody / CD11b / ITGAM

CAT: 0800-R31561Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31561Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Macrophage-1 alpha (MAC-1) or CD11b are glycoproteins encoded by the ITGAM gene. It is mapped to 16p11.2. MAC-1 has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Additionally, it likely recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Flow cytometry: 1-3ug/10^6 cells
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Human partial recombinant protein (AA 17-382) was used as the immunogen for this MAC-1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the MAC-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This MAC-1 antibody is available for research use only.
Storage Conditions
After reconstitution, the MAC-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the MAC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.1. This antibody has shown cross-reactivity with CD11c by ELISA.
Location
Cytoplasmic, membranous
Image Legend
IHC-P: MAC-1 antibody testing of FFPE human tonsil tissue

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Alternative Products

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GTR18571976CD11b Antibody / MAC-1 / ITGAM
BNUM3338-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), 1mg/mL
BNUM3339-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3339), 1mg/mL
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BNUM3337-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), 1mg/mL
BNUM3340-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3340), 1mg/mL
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BNUB0271-500CD11b / MAC-1 (Microglial Marker) (ITGAM/271), 0.2mg/mL
BNUB3338-100CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), 0.2mg/mL

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