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CD11b Antibody / MAC-1 / ITGAM

CAT: 0800-V3528-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V3528-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3) . Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2 µg/mL
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human CD11b/ITGAM protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ITGAM/271
Applications
FACS, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CD11b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD11b antibody is available for research use only.
Storage Conditions
Store the CD11b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11b antibody to be titered up or down for optimal performance.
Location
Cell surface, cytoplasm
Image Legend
SDS-PAGE Analysis of Purified, BSA-Free CD11b Antibody (clone ITGAM/271) . Confirmation of Integrity and Purity of the Antibody.

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Alternative Products

CatalogName
GTR18571976CD11b Antibody / MAC-1 / ITGAM
BNUM3338-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), 1mg/mL
BNUM3339-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3339), 1mg/mL
BNUM0271-50CD11b / MAC-1 (Microglial Marker) (ITGAM/271), 1mg/mL
BNUM3337-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), 1mg/mL
BNUM3340-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3340), 1mg/mL
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BNUB0271-500CD11b / MAC-1 (Microglial Marker) (ITGAM/271), 0.2mg/mL
BNUB3338-100CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), 0.2mg/mL

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