Products for Research Use Only
RegisterLogin

CD11b Antibody / MAC-1 / ITGAM

CAT: 0013-GTR18571976Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18571976Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3) . Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
Reactivity
Human, Mouse
Immunogen
B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody.
Clonality
Monoclonal
Clone
M1/70
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2ug/ml, Functional studies (order BSA/sodium azide-free format)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11b antibody to be titered up or down for optimal performance.
Tested Applications
FACS, Functional Studies, IF
Host or Source
Rat
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rat IgG2b, kappa

Related Products

CatalogName
GTR18575000CD11b Antibody / MAC-1
GTR18082844-01CD11b Antibody / MAC-1
GTR18225322ITGAM/CD11b Antibody
GTR18222061ITGAM/CD11b Antibody
GTR18044860-01CD11b/ITGAM polyclonal antibody
GTR18694790-01CD11b/ITGAM Monoclonal Antibody
GTR18205185-01CD11b / MAC-1 (Microglial Marker) Antibody
GTR18695283-01CD11b/ITGAM Mouse Monoclonal Antibody
GTR18694792-01CD11b/ITGAM Rat Monoclonal Antibody
GTR18691012-01CD11b/ITGAM Monoclonal Antibody (PE)

Alternative Products

CatalogName
V3528SAF-100UGCD11b Antibody / MAC-1 / ITGAM
R31561MAC-1 Antibody / CD11b / ITGAM
R32580Mouse CD11b Antibody / MAC-1 / ITGAM
R20316-0.1MLRecombinant CD11b Antibody / MAC-1 / ITGAM / C-Terminal
BNUM3338-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3338), 1mg/mL
BNUM3339-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3339), 1mg/mL
BNUM0271-50CD11b / MAC-1 (Microglial Marker) (ITGAM/271), 1mg/mL
BNUM3337-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3337), 1mg/mL
BNUM3340-50CD11b / MAC-1 (Microglial Marker) (ITGAM/3340), 1mg/mL
V7888SAF-100UGCD11b Antibody / MAC-1

Popular Products