IGF2R Antibody

• Description:

  Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

• Specifications:

  Western blot: 1:1000-2000

• Gene ID:

  3482

• UniProt:

  P11717

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 2424-2458 from the human protein was used as the immunogen for the IGF2R antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the IGF2R antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This IGF2R antibody is available for research use only.

• Storage Conditions:

  Aliquot the IGF2R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the IGF2R antibody may be required due to differences in protocols and substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human 1) 293T/17, 2) HeLa and 3) Jurkat cell lysate with IGF2R antibody at 1:2000. Predicted molecular weight: 274 kDa.