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Ar-Turmerone

CAT: 0804-HY-N6703-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6703-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ar-Turmerone ((+) -ar-Turmerone) is an orally active and major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities. ar-Turmerone induces apoptosis in U937 cells. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation in vitro and in vivo, and can be used for various neurologic disorders study[1][2][3][4][5].
CAS Number
532-65-0
Product Name Alternative
(+) -ar-Turmerone
UNSPSC
12352005
Hazard Statement
H317, H319, H411
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ar-turmerone.html
Purity
99.00
Solubility
Ethanol : 50 mg/mL (ultrasonic)
Smiles
CC1=CC=C(C=C1)[C@H](CC(/C=C(C)\C)=O)C
Molecular Formula
C15H20O
Molecular Weight
216.32
Precautions
H317, H319, H411
References & Citations
[1]Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43 (5) :526-31.|[2]Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48 (8-9) :2011-20.|[3]Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42 (2) :96-100.|[4]Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR) . Hum Vaccin Immunother. 2012 Oct;8 (10) :1416-24.|[5]Zhou W, et al. Structural optimization of naturally derived Ar-turmerone, as novel neuroinflammation suppressors effective in an Alzheimer mouse model. Bioorg Med Chem. 2025 Jan 1;117:118014.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported