B-Raf IN 18

B-Raf IN 18

• CAS Number: 1244644-50-5
• UNSPSC Description: B-Raf IN 18 (compound 26) is a B-Raf inhibitor, with IC50 of 3.8 nM. B-Raf IN 18 can be used in anti-cancer related research[1].
• Target Antigen: Raf
• Type: Reference compound
• Related Pathways: MAPK/ERK Pathway
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/b-raf-in-18.html
• Smiles: O=S(C1=C(C=CC=C1F)F)(NC2=CC=CC(C3=C(SC(C(C)C)=N3)C4=NC(NC5=CC=C(N=C5)N6CCOCC6)=NC=C4)=C2F)=O
• Molecular Weight: 667.72
• References & Citations: [1]Stellwagen JC,et al. Development of potent B-RafV600E inhibitors containing an arylsulfonamide headgroup. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4436-40.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported