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B-Raf IN 14

CAT: 0804-HY-153914Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153914Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
B-Raf IN 14 (Comp 25) is a BRAF inhibitor with IC50 value of 11.08 μM, which can be used in cancer-related research[1].
CAS Number
326918-98-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/b-raf-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C(N)CSC(N1CC2=CC=CC(Br)=C2)=NC(N(C)C(N3)=O)=C1C3=O
Molecular Formula
C15H14BrN5O3S
Molecular Weight
424.27
Precautions
H302, H315, H319
References & Citations
[1]Cheng Luo, et al. Identification of BRAF inhibitors through in silico screening. J Med Chem. 2008 Oct 9;51 (19) :6121-6127.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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