B-Raf IN 5

• Target:

  Others|||Raf

• Related Pathways:

  MAPK|||Others

• Bioactivity:

  B-Raf IN 5 is a potent inhibitor of the protein kinase B-Raf (IC50: 2.0 nM) . B-Raf IN 5 resists rapid metabolism and does not bind to the secondary target PXR.

• Smiles:

  FC1=C(C2=C(SC(=N2)C3COCCN3)C4=NC(N)=NC=C4)C=C(Cl)C=C1NS(=O)(=O)C5=C(F)C=CC(F)=C5

• Molecular Formula:

  C23H18ClF3N6O3S2

• Molecular Weight:

  583.01

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2648698-30-8