B-Raf IN 8

CAT: 0931-T60727-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T60727-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1215313-19-1

Target

Others, Raf

Related Pathways

Others, MAPK

Bioactivity

B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC50 = 70.65 nM) with antitumor activity, demonstrating IC50 values of 9.78, 13.78, 18.52, and 29.85 μM against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7), and human prostate cancer (PC-3) cells [1].

Smiles

N(=CC1=CC=C(OC)C=C1)C2=CC=C(C=C2)C=3CCC(=O)NN3

Molecular Formula

C18H17N3O2

Molecular Weight

307.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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