B-Raf IN 8

• Target:

  Others|||Raf

• Related Pathways:

  Others|||MAPK

• Bioactivity:

  B-Raf IN 8 (compound 7g) is a potent inhibitor of B-Raf (IC50 = 70.65 nM) with antitumor activity, demonstrating IC50 values of 9.78, 13.78, 18.52, and 29.85 ?M against hepatocellular carcinoma (HEPG-2), colon carcinoma (HCT-116), mammary gland (MCF-7), and human prostate cancer (PC-3) cells [1].

• Smiles:

  N(=CC1=CC=C(OC)C=C1)C2=CC=C(C=C2)C=3CCC(=O)NN3

• Molecular Formula:

  C18H17N3O2

• Molecular Weight:

  307.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1215313-19-1