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LSD1-IN-24

CAT: 0804-HY-149213-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149213-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSD1-IN-24 (compound 3S) is a selective LSD1 inhibitor with IC50 = 0.247 μM. LSD1-IN-24 can mediate the expression of PD-L1, enhance T cell killing response, and can be used in cancer research[1].
CAS Number
4734-59-2
UNSPSC
12352005
Target
Histone Demethylase; PD-1/PD-L1
Type
Reference compound
Related Pathways
Epigenetics; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-24.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
N1(CCN2C3=C(SC4=C2C=CC=C4)C=CC=C3)CCOCC1
Molecular Formula
C18H20N2OS
Molecular Weight
312.43
References & Citations
[1]Xing-Jie Dai, et al. Phenothiazine-Based LSD1 Inhibitor Promotes T-Cell Killing Response of Gastric Cancer Cells. J Med Chem. 2023 Mar 23;66 (6) :3896-3916.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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