MS-444
CAT:
804-HY-100685-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MS-444
- CAS Number: 150045-18-4
- UNSPSC Description: MS-444 inhibits the activity of purified smooth muscle myosin light chain kinase (MLCK) with an IC50 value of 10 μM.
- Target Antigen: Myosin
- Type: Reference compound
- Related Pathways: Cytoskeleton
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/MS-444.html
- Purity: 99.45
- Solubility: DMSO : 50 mg/mL (ultrasonic)|N-Methylpyrrolidone (NMP) : 20 mg/mL (ultrasonic)
- Smiles: O=C(C1=C(C)OC=C1C2)C3=C2C(O)=CC=C3O
- Molecular Weight: 230.22
- References & Citations: [1]Satoshi Nakanishi. et al. MS-444, a new inhibitor of myosin light chain kinase from Micromonosporasp.KY7123. The Journal Of Antibiotics. 1995,48(9):948-951.|[2]Fernando F. Blanco.et al, Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. Oncotarget. 2016 Nov 8; 7(45): 74043-74058.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported