MNI-444

• UNSPSC Description:

  MNI-444 is a BBB-penetrable ligand of adenosine 2A receptor (A2AR). A2AR is a potential non-dopaminergic target for the research of Parkinson’s disease[1].

• Target Antigen:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mni-444.html

• Smiles:

  NC1=NC(N(CCN2CCN(C3=CC=C(OCCF)C=C3)CC2)N=C4)=C4C5=NC(C6=CC=CO6)=NN15

• Molecular Weight:

  491.52

• References & Citations:

  [1]Barret O, et al. Characterization in humans of 18F-MNI-444, a PET radiotracer for brain adenosine 2A receptors. J Nucl Med. 2015 Apr;56(4):586-91.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1974301-94-4