MS 245

• Description :

  MS 245 is an antagonist of the 5-HT6 receptor wih an Ki value of 1.5 nM[1].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ms-245.html

• Smiles :

  O=S(N(C1=CC=C(OC)C=C21)C=C2CCN(C)C)(C3=CC=CC=C3)=O

• Molecular Formula :

  C19H22N2O3S

• Molecular Weight :

  358.45

• References & Citations :

  [1]Manik Pullagurla, et al. Modulation of the stimulus effects of (+) amphetamine by the 5-HT6 antagonist MS-245. Modulation of the stimulus effects of (+) amphetamine by the 5-HT6 antagonist MS-245. Pharmacol Biochem Behav. 2004 Jun;78 (2) :263-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT6 Receptor; MUC2

• CAS Number :

  [263384-65-2]