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STAT6 Recombinant Protein

CAT: 223-92-166Size: 0.05 mgDry Ice: NoHazardous: No
0.05 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT family of transcription factors. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT6 plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. STAT6 has been shown to interact with EP300, CREB-binding protein, NFKB1, Nuclear receptor coactivator 1, IRF4 and SND1.
CAS Number
9000-83-3
NCBI Gene ID
6778
Swiss Prot
P42226
Accession Number
P42226
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
23.9 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Signal transducer and activator of transcription 6
NCBI Organism
Homo sapiens
Other Product Names
Signal Transducer and Activator of Transcription 6, IL-4 Stat, STAT6
Species
Human
Protein ID
578833707
Physical Properties
Lyophilized

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