Products for Research Use Only

STAT1 Recombinant Protein

CAT: 0223-92-079Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-92-079Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.
CAS Number
9000-83-3
NCBI Gene ID
6772
Swiss Prot
P42224
Accession Number
P42224
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Homeostasis, Signal Transduction, Other, Inflammasomes
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
83.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Signal transducer and activator of transcription 1
NCBI Organism
Homo sapiens
Other Product Names
Signal Transducer and Activator of Transcription 1-Alpha/Beta, Transcription Factor ISGF-3 Components p91/p84, STAT1, ISGF-3
Species
Human
Protein ID
578833707
Physical Properties
Lyophilized