Products for Research Use Only
RegisterLogin

7-Nitroindazole (sodium)

CAT: 0804-HY-69019ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-69019ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
7-Nitroindazole sodium is a selective and BBB-penetrable inhibitor of nitric oxide synthase (NOS) . 7-Nitroindazole sodium can inhibit the activity of central NOS with an IC50 of 0.47 μM in the cerebellum of mice. 7-Nitroindazole sodium has anti-injurious and neuroprotective properties[1][2].
CAS Number
161467-34-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/7-nitroindazole-sodium.html
Smiles
O=[N+](C1=CC=CC2=C1[N-]N=C2)[O-].[Na+]
Molecular Formula
C7H4N3NaO2
Molecular Weight
185.12
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Moore PK, et al. 7-Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti-nociceptive activity in the mouse without increasing blood pressure. Br J Pharmacol. 1993 Feb;108 (2) :296-7.|[2]Moore PK, et al. Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects. Br J Pharmacol. 1993 Sep;110 (1) :219-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

7-Nitroindazole sodium salt
CAS Number161467-34-1
PubChem CID23661758
IUPAC Namesodium 7-nitroindazol-2-ide
Molecular FormulaC7H4N3NaO2
Molecular Weight185.12
Topological Polar Surface Area59.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Heavy Atom Count13
Formal Charge0
Complexity192
SMILES
C1=CC2=C[N-]N=C2C(=C1)[N+](=O)[O-].[Na+]
InChI
InChI=1S/C7H4N3O2.Na/c11-10(12)6-3-1-2-5-4-8-9-7(5)6;/h1-4H;/q-1;+1
InChIKey
DJMLKKIIBMJGIQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-Nitroindazole sodium salt
CAS: 161467-34-1
CID: 23661758
Formula: C7H4N3NaO2
MW: 185.12
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight185.12
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass185.02012066
Monoisotopic Mass185.02012066
Topological Polar Surface Area59.7 Ų
Heavy Atom Count13
Formal Charge0
Complexity192
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-69019-017-Nitroindazole
HY-101175-013-Bromo-7-nitroindazole
HY-130569A7-Hydroxymethotrexate (sodium)
HY-132144A7-Deaza-7-propargylamino-dGTP (sodium)
HY-137099AGenistein 7-sulfate (sodium)
HY-130569S7-Hydroxymethotrexate-d3 (sodium)
HY-W001974-017-Nitroindole
HY-100811A-017-Chlorokynurenic acid (sodium salt)
HY-126855A-01Cholic acid 7-sulfate (sodium)
HY-100834A5,7-Dichlorokynurenic acid (sodium)

Alternative Products

CatalogName
sc-2211147-Nitroindazole sodium salt
sc-220856B3-Bromo-7-nitroindazole sodium salt
GFA257077-Aminoceftriaxone sodium
PC4669Sodium 7-chloroperfluoroheptanoate
GTR19281186-017-Hydroxymethotrexate sodium
TSW-00861-017-Deaza-7-propargylamino-dGTP sodium
AR-C02174-017-Amino Ceftriaxone Sodium (7-ACT)
N0530-26ASodium channel Nav1.7
RM-C131407-01Cefminox Sodium Impurity 7
RM-P201633-01Pantoprazole Sodium Impurity 7

Popular Products