Lu AF11205

CAT: 0804-HY-117697Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-117697Size:1 Each
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Description
Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors.
CAS Number
[1290133-16-2]
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lu-af11205.html
Smiles
O=C(N1CCCCC1)C2=CN=C(S2)C#CC3=CC=CC=C3
Molecular Formula
C17H16N2OS
Molecular Weight
296.39
References & Citations
[1]Fused thiazolyl alkynes as potent mGlu5 receptor positive allosteric modulators
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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