Lu AF11205

• UNSPSC Description:

  Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors.

• Target Antigen:

  mGluR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/lu-af11205.html

• Smiles:

  O=C(N1CCCCC1)C2=CN=C(S2)C#CC3=CC=CC=C3

• Molecular Weight:

  296.39

• References & Citations:

  [1]Fused thiazolyl alkynes as potent mGlu5 receptor positive allosteric modulators

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1290133-16-2