PPAR agonist 5

CAT: 0804-HY-163547-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-163547-01Size:5 mg
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Description
PPAR agonist 5 (compound 4b) is a potent PPAR agonist with EC50 values of 3.20, 1.51, 1.92 µM for PPARα, PPARβ/δ, PPARγ, respectively. PPAR agonist 5 shows anti-inflammatory effect[1].
CAS Number
[3059387-62-8]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ppar-agonist-5.html
Purity
97.16
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(OCC)CC/C(C)=C/CCC1=NC2=CC=C(OCC3=CC=CC=C3)C=C2C=C1
Molecular Formula
C26H29NO3
Molecular Weight
403.51
References & Citations
[1]Villarroel-Vicente C, et al. Synthesis of a new 2-prenylated quinoline as potential drug for metabolic syndrome with pan-PPAR activity and anti-inflammatory effects. Bioorg Med Chem Lett. 2024 Jul 1;106:129770.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARα; PPARβ/δ; PPARγ

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