eIF4A3-IN-2
CAT:
804-HY-101785-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
eIF4A3-IN-2
- CAS Number: 2095677-20-4
- UNSPSC Description: eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1].
- Target Antigen: Autophagy; Eukaryotic Initiation Factor (eIF)
- Type: Reference compound
- Related Pathways: Autophagy;Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/eIF4A3-IN-2.html
- Purity: 99.70
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=C(Br)C=C1)N2CCN(C(C3=C4N(C=C(Br)C=C4)N=C3)=O)C[C@@H]2C5=CC=C(Cl)C=C5
- Molecular Weight: 602.70
- References & Citations: [1]Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017 Jul 21;12(7):1760-1768.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported