EIF4A3-IN-6

• Description:

  EIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-6 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) [1].

• UNSPSC:

  12352005

• Target:

  Eukaryotic Initiation Factor (eIF)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/eif4a3-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@]12[C@](OC3=CC(OC)=NC(OC)=C32)(C4=CC=C(C=C4)C#N)[C@@](C5=CC=CC=C5)([H])[C@H]([C@H]1O)CN

• Molecular Formula:

  C26H25N3O5

• Molecular Weight:

  459.49

• References & Citations:

  [1]Justin T. Ernst, et al. Eif4a-inhibiting compounds and methods related thereto. Patent US20170145026A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  EIF4

• CAS Number:

  [2100133-77-3]