eIF4A3-IN-5

eIF4A3-IN-5

• CAS Number: 2100145-31-9
• UNSPSC Description: eIF4A3-IN-5 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-5 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1)[1].
• Target Antigen: Eukaryotic Initiation Factor (eIF)
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/eif4a3-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@]12[C@](OC3=CC(OC)=NC(OC)=C32)(C4=CC=C(C=C4)C#N)[C@@](C5=CC=CC=C5)([H])[C@H]([C@H]1O)C(O)=O
• Molecular Weight: 474.46
• References & Citations: [1]Justin T. Ernst, et al. Eif4a-inhibiting compounds and methods related thereto. Patent US20170145026A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported