EIF4A3-IN-5

• Description :

  EIF4A3-IN-5 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-5 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) [1].

• UNSPSC :

  12352005

• Target :

  Eukaryotic Initiation Factor (eIF)

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/eif4a3-in-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@]12[C@](OC3=CC(OC)=NC(OC)=C32)(C4=CC=C(C=C4)C#N)[C@@](C5=CC=CC=C5)([H])[C@H]([C@H]1O)C(O)=O

• Molecular Formula :

  C26H22N2O7

• Molecular Weight :

  474.46

• References & Citations :

  [1]Justin T. Ernst, et al. Eif4a-inhibiting compounds and methods related thereto. Patent US20170145026A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  EIF4

• CAS Number :

  [2100145-31-9]