Products for Research Use Only
RegisterLogin

PF-998425

CAT: 0804-HY-14250-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14250-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PF-998425 is a potent, selective nonsteroidal androgen receptor (AR) antagonist with an IC50 of 37 nM and 43 nM in AR binding and cellular assays, respectively. PF-998425 has low activity on common receptors and enzymes, such as progesterone receptor. PF-998425 can be used for sebum control and androgenetic alopecia research[1].
CAS Number
1076225-27-8
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/pf-998425.html
Purity
98.31
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@H](CCCC1)C2=CC(C(F)(F)F)=C(C=C2)C#N
Molecular Formula
C14H14F3NO
Molecular Weight
269.26
Precautions
H302, H319
References & Citations
[1]Jie Jack Li, et al. Rational design and synthesis of 4- ((1R,2R) -2-hydroxycyclohexyl) -2 (trifluoromethyl) benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008 Nov 13;51 (21) :7010-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P991635PF-07329640
HY-P990645-01PF-03732010
HY-171821-01PF-08046054
HY-123803PF-06807656
HY-120195PF-04677490
HY-108338PF-05139962
HY-108327PF-05020182
HY-19530-01PF-2771
HY-10721-01PF-AKT400
HY-125415-01PF-4693627

Alternative Products

CatalogName
B7536-10PF 998425
P294060PF-998425
MBS5802674(Rac)-PF-998425
T38467(Rac) -PF-998425
MBS579460PF-03084014 (PF-3084014)
BA5950-5.1PF-06928215
BA7028-5PF-4840154
B5563-10PF 5081090
BA8315-10PF-06747711
C4756-10PF-622

Popular Products