USP8-IN-2

USP8-IN-2

• CAS Number: 2477651-11-7
• UNSPSC Description: USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].
• Target Antigen: Deubiquitinase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/usp8-in-2.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: FC(F)(C1=NC(N2CCC(CC2)NC(NC3=CC(Cl)=CC=C3OC)=S)=CC=C1)F
• Molecular Weight: 444.90
• References & Citations: [1]Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported