USP8-IN-1

• UNSPSC Description:

  USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82.04 μM (CN111138358A; U10)[1].

• Target Antigen:

  Deubiquitinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/usp8-in-1.html

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  [O-][N+](C1=CC=C(NC(N2CCN(CC2)C3=CC=C(C=C3N)OC)=S)C=C1)=O

• Molecular Weight:

  387.46

• References & Citations:

  [1]Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2477650-96-5