Org-31710

CAT: 0804-HY-118257Size: InquireDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-118257Size:Inquire

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

118968-41-5

UNSPSC Description

Org-31710 is a specific progesterone receptor (PR) inhibitor. Org-31710 shows antiprogestational effect. Org 31710 abolishes the Folic acid (HY-16637)-regulated proliferation and migration in PR positive cancer cell lines. Org 31710 abolishes the folic acid-increased the levels of p-PRA, p-PRB, and p-cSrcY416[1][2].

Target Antigen

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/org-31710.html

Smiles

C[C@@]12[C@](CC[C@@]23CCCO3)([H])[C@@]4([H])C([C@@H](C5=CC=C(C=C5)N(C)C)C1)=C6C([C@@H](C4)C)=CC(CC6)=O

Molecular Weight

445.64

References & Citations

[1]Mizutani T, et al. Novel antiprogestins Org 31806 and 31710: interaction with mammalian progesterone receptor and DNA binding of antisteroid receptor complexes. J Steroid Biochem Mol Biol. 1992 Aug;42(7):695-704. |[2]Wang HC, et al. Activation of progesterone receptor is essential for folic acid-regulated cancer cell proliferation and migration. J Nutr Biochem. 2023 Feb;112:109205.

Shipping Conditions

Room temperature

Clinical Information

Phase 1

Related Products

Catalog	Name
HY-P2113	ORG-2766
HY-120029	Org-9935
HY-105911	Org 6582
HY-19410	ORG-25435
HY-118152-01	Org-12962
HY-P0037	Org-30850
HY-107527A	Org 25543
HY-106965	Org 21465
HY-106838A	Org 6906
HY-13288-01	Org 27569

Alternative Products

Catalog	Name
GTR19196852-01	Org-31710
B7169-50	Org 20599
B5717-50	Org 37684
BA6764-10	Org-26576
B1426-5.1	Org 27569
563319	Org-37684
ZMB58840-01	ORG 25935
T71041-01	Org 9935
T202145-01	ORG-28611
T28262-01	Org-29647

Org-31710

Related Products

Alternative Products

Popular Products