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Org 6582

CAT: 0804-HY-105911Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105911Size:1 Each
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Description
Org 6582 is a competitive, selective, and long-acting 5-HT (Ki = 89 nM) uptake inhibitor. Org 6582’s inhibitory effect on 5-HT uptake can last for more than 48 hours. Org 6582 can be used for research on depressive disorders[1].
CAS Number
59905-71-4
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
[H][C@]1(N)[C@]2([H])C3=CC=C(Cl)C=C3C[C@@]1([H])C=CC2.Cl
Molecular Formula
C13H15Cl2N
Molecular Weight
256.17
References & Citations
[1]Mireylees SE, et al. Effects of ORG 6582 on monoamine uptake in vitro. Biochem Pharmacol. 1978 Apr 1;27 (7) :1023-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Org 6582

inhibits 3-hydroxytryptamine reuptake; RN & NM refer to HCl

CAS Number59905-71-4
PubChem CID133082267
IUPAC Name(1S,9S,13R)-5-chlorotricyclo[7.3.1.02,7]trideca-2(7),3,5,10-tetraen-13-amine;hydrochloride
Molecular FormulaC13H15Cl2N
Molecular Weight256.17
Topological Polar Surface Area26
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Heavy Atom Count16
Formal Charge0
Complexity276
SMILES
C1C=C[C@@H]2CC3=C([C@H]1[C@@H]2N)C=CC(=C3)Cl.Cl
InChI
InChI=1S/C13H14ClN.ClH/c14-10-4-5-11-9(7-10)6-8-2-1-3-12(11)13(8)15;/h1-2,4-5,7-8,12-13H,3,6,15H2;1H/t8-,12+,13-;/m1./s1
InChIKey
LWRJZIPAGMGXQJ-POJHVLMBSA-N
Chemical Structure
2D Structure
2D structure of Org 6582
CAS: 59905-71-4
CID: 133082267
Formula: C13H15Cl2N
MW: 256.17
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight256.17
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass255.0581549
Monoisotopic Mass255.0581549
Topological Polar Surface Area26 Ų
Heavy Atom Count16
Formal Charge0
Complexity276
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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