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Org 21465

CAT: 0804-HY-106965Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106965Size:1 Each
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Description
Org 21465 is an agent that can relieve pain. Org 21465 causes no cardiovascular or respiratory depression. Org 21465 can inhibit GABAA receptor in vivo[1][2].
CAS Number
167946-96-5
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/org-21465.html
Smiles
C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@H]([C@@H](N4CC(C)(OCC4)C)C2)O)([H])[C@@]5([H])[C@](CC3=O)([C@H](CC5)C(C)=O)C
Molecular Formula
C27H43NO4
Molecular Weight
445.63
References & Citations
[1]Vanlersberghe C, et, al. Etomidate and other non-barbiturates. Handb Exp Pharmacol. 2008: (182) :267-82. |[2]Visser SAG, et, al. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA (A) receptor in vivo. J Pharmacol Exp Ther. 2002 Nov;303 (2) :616-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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