Org 21465

• Description:

  Org 21465 is an agent that can relieve pain. Org 21465 causes no cardiovascular or respiratory depression. Org 21465 can inhibit GABAA receptor in vivo[1][2].

• UNSPSC:

  12352005

• Target:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/org-21465.html

• Smiles:

  C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@H]([C@@H](N4CC(C)(OCC4)C)C2)O)([H])[C@@]5([H])[C@](CC3=O)([C@H](CC5)C(C)=O)C

• Molecular Formula:

  C27H43NO4

• Molecular Weight:

  445.63

• References & Citations:

  [1]Vanlersberghe C, et, al. Etomidate and other non-barbiturates. Handb Exp Pharmacol. 2008: (182) :267-82. |[2]Visser SAG, et, al. Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA (A) receptor in vivo. J Pharmacol Exp Ther. 2002 Nov;303 (2) :616-26.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  [167946-96-5]