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AZD-6605

CAT: 0804-HY-119185Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119185Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD-6605 is a potent, reversible inhibitor of MMP2, MMP9, MMP12 and MMP13 with excellent selectivity. During drug development, AZD-6605 was optimized for activity, solubility and DMPK properties against MMP13 by replacing the zinc hydroxide binding group associated with historical inhibitors[1].
CAS Number
893556-15-5
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azd-6605.html
Smiles
O=C1NC([C@](C)(N1)CS(=O)(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(C(F)F)F)=O)=O
Molecular Formula
C18H21F4N3O6S
Molecular Weight
483.43
References & Citations
[1]Hydantoin based inhibitors of MMP13--discovery of AZD6605
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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