AZD-9819

• Description:

  AZD-9819 is a neutrophil elastase (HNE) inhibitor. AZD-9819 can be used to study chronic obstructive pulmonary disease[1].

• UNSPSC:

  12352005

• Target:

  Elastase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(C1=NC(C2=CC=NN2C3=CC=C(C#N)C=C3)=C(C)N(C4=CC=CC(C(F)(F)F)=C4)C1=O)NCC

• Molecular Formula:

  C25H19F3N6O2

• Molecular Weight:

  492.45

• References & Citations:

  [1]Gu C, et al. Lipid Peroxide-Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples. Drug Metab Dispos. 2015 Oct;43 (10) :1441-9.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  [956907-23-6]