AZD-7295

• Description:

  AZD-7295 is a HCV NS5A protein inhibitor, with an EC50 of 7 nM for GT-1b replicon[1][2].

• UNSPSC:

  12352005

• Target:

  HCV Protease

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/azd-7295.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C2=CC(NC(C3CC3)=O)=CC=C2OC(F)(F)F)C=C1)NC4=CC=C(CN5CCN(S(=O)(CCC)=O)CC5)C=C4

• Molecular Formula:

  C32H35F3N4O5S

• Molecular Weight:

  644.70

• References & Citations:

  [1]Erik De Clercq, et al. Current race in the development of DAAs (direct-acting antivirals) against HCV. Biochem Pharmacol. 2014 Jun 15;89 (4) :441-52.|[2]Min Gao, et al. Antiviral activity and resistance of HCV NS5A replication complex inhibitors. Curr Opin Virol. 2013 Oct;3 (5) :514-20.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  [929890-64-2]