AZD-4818

CAT: 0804-HY-15545-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15545-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD-4818 is a potent, orally active antagonist of chemokine CCR1. AZD-4818 can be used for researching chronic obstructive pulmonary disease (COPD) [1].
CAS Number
[1003566-93-5]
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/azd-4818.html
Purity
99.10
Solubility
DMSO : 50 mg/mL (ultrasonic; adjust pH to 2 with HCl)
Smiles
CNC(C(C=C(C(OC(C)(C)C(O)=O)=C1)Cl)=C1OC[C@@H](O)CN2CCC3(CC2)OC4=CC=C(Cl)C=C4C3)=O
Molecular Formula
C27H32Cl2N2O7
Molecular Weight
567.46
References & Citations
[1]Norman P. AZD-4818, a chemokine CCR1 antagonist: WO2008103126 and WO2009011653. Expert Opin Ther Pat. 2009;19 (11) :1629-1633.|[2]Kerstjens HA, et al., Tolerability and efficacy of inhaled AZD4818, a CCR1 antagonist, in moderate to severe COPD patients. Respir Med. 2010 Sep;104 (9) :1297-303.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
CCR1

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