Galectin-3-IN-5

• UNSPSC Description:

  Galectin-3-IN-5 (Compound 20) is an orally active inhibitor of galectin-3 (Gal-3), with an IC50 value of 9.2 nM against hGal-3[1].

• Target Antigen:

  Galectin

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/galectin-3-in-5.html

• Smiles:

  CN1N=C(N(C2=C(C(F)(F)F)C=CC(Cl)=C2)C1=S)[C@@H]3O[C@@H]([C@@H]([C@H](N4C=C(C5=C(C(F)=C(C=C5)Br)F)N=N4)[C@H]3O)O)CO

• Molecular Weight:

  697.86

• References & Citations:

  [1]Yoon D S, et al. Atropisomerism Observed in Galactose-Based Monosaccharide Inhibitors of Galectin-3 Comprising 2-Methyl-4-phenyl-2, 4-dihydro-3 H-1, 2, 4-triazole-3-thione[J]. Journal of Medicinal Chemistry, 2024.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported