Galectin-3-IN-7

• Description:

  Galectin-3-IN-7 is a selective Galectin-3 inhibitor with a Kd of 5.7 nM and shows 390-fold selectivity over Gal-1. Galectin-3-IN-7 can downregulate profibrotic signaling such as ACTA2, COL1A2, and FN1 in TGFβ-stimulated LX2 hepatic stellate cells. Galectin-3-IN-7 can be used for the research of fibrosis[1].

• UNSPSC:

  12352005

• Target:

  Galectin

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Others

• Smiles:

  O=C(C1=CC2=C(C(N([C@H]3[C@H](O)[C@@H](O)[C@H](S[C@H]4[C@H](O)[C@@H](N5N=NC(C6=CC=CC(F)=C6)=C5)[C@@H](O)[C@@H](CO)O4)[C@@H](CO)O3)C(C)=O)=C1)C=CN2)O

• Molecular Formula:

  C31H34FN5O11S

• Molecular Weight:

  703.69

• References & Citations:

  NN

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Galectin-3