Galectin-3-IN-2

• UNSPSC Description:

  Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of galectin-3 (Gal-3; IC50=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes[1]. Galectin-3-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  Galectin

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/galectin-3-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@@H]([C@H]([C@@H](O[C@@H]1CO)S[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)OCC3=CN(N=N3)C4=CC=C(C=C4)F)O)O)OCC#C

• Molecular Weight:

  571.57

• References & Citations:

  [1]David Vrbata, et al. Glycopolymers Decorated with 3- O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3. J Med Chem. 2022 Mar 10;65(5):3866-3878.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2883648-71-1