Galectin-3-IN-2

Galectin-3-IN-2

• CAS Number: 2883648-71-1
• UNSPSC Description: Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of galectin-3 (Gal-3; IC50=8.3 μM). Galectin-3 participates in many cancer-related metabolic processes[1]. Galectin-3-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: Galectin
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/galectin-3-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@@H]([C@H]([C@@H](O[C@@H]1CO)S[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)OCC3=CN(N=N3)C4=CC=C(C=C4)F)O)O)OCC#C
• Molecular Weight: 571.57
• References & Citations: [1]David Vrbata, et al. Glycopolymers Decorated with 3- O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3. J Med Chem. 2022 Mar 10;65(5):3866-3878.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported