DNMT3L antibody

CAT: 0710-FNab02486Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab02486Size:100 µg
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Background
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Synonyms
DNA (cytosine-5) -methyltransferase 3-like|DNMT3L
Gene ID
29947
UniProt
Q9UJW3
Host
Rabbit
Reactivity
Human
Immunogen
DNA (cytosine-5-) -methyltransferase 3-like
Target
DNMT3L
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kD and 70kd
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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