DNMT3A antibody

• Background:

  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

• Synonyms:

  DNA (cytosine-5) -methyltransferase 3A (Dnmt3a) |Cysteine methyltransferase DNMT3A|DNA methyltransferase HsaIIIA (DNA MTase HsaIIIA, M.HsaIIIA) |DNMT3A

• Gene ID:

  1788

• UniProt:

  Q9Y6K1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  DNA (cytosine-5-) -methyltransferase 3 alpha

• Target:

  DNMT3A

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Epigenetics, Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  95 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF