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CXCR1 antibody

CAT: 0710-FNab02099Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab02099Size:100 µg
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Background
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Synonyms
C-X-C chemokine receptor type 1 (CXC-R1, CXCR-1) |CDw128a|High affinity interleukin-8 receptor A (IL-8R A) |IL-8 receptor type 1|CXCR1|CMKAR1|IL8RA
Gene ID
3577
UniProt
P25024
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Interleukin 8 receptor, alpha
Target
CXCR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Stem Cells, Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP
Immunogen Sequence
Peptide, C-terminal

UniProtKB · P25024

C-X-C chemokine receptor type 1

CXCR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P25024
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CXCR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CXC-R1, CXCR-1
EC number
—
Processing
—
Secondary accessions
B2R6Q3, Q2YEF8, Q2YEG4, Q2YEG5, Q2YEG7, Q2YEG8, Q53R18, Q6IN95, Q8N6T6, Q9P2T8, Q9P2T9, Q9P2U0, Q9P2U1, Q9P2U2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

Biological process

Chemotaxis

PTM

Disulfide bondGlycoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

TransmembraneTransmembrane helix

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