CXCR4 antibody
CAT:
710-FNab02102
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CXCR4 antibody
- Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Synonyms: C-X-C chemokine receptor type 4 (CXC-R4, CXCR-4)|FB22|Fusin|HM89|LCR1|Leukocyte-derived seven transmembrane domain receptor (LESTR)|Lipopolysaccharide-associated protein 3 (LAP-3, LPS-associated protein 3)|NPYRL|Stromal cell-derived factor 1 receptor (SDF-1 receptor)|CXCR4
- CAS Number: 9007-83-4
- Gene ID: 7852
- UniProt: P61073
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: chemokine (C-X-C motif) receptor 4
- Target: CXCR4
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Field of Research: Signal Transduction, Immunology, Developmental biology, Neuroscience, Stem Cells
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 60 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)