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YM-49598 (iodide)

CAT: 0804-HY-119005ASize: 1 EachDry Ice: NoHazardous: No
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Description
YM-49598 iodide is a tachykinin NK-1 receptor antagonist. YM-49598 iodide can inhibit drug-induced bladder contraction in rats, with IC50 of 11 μg/kg[1].
CAS Number
476494-44-7
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ym-49598-iodide.html
Smiles
CC(C)OC1=CC(CC(N2CC(C3=CC=C(C(Cl)=C3)Cl)(CCC2)CC[N+]4(CCC(CC4)C5=CC=CC=C5)C)=O)=CC=C1.[I-]
Molecular Formula
C36H45Cl2IN2O2
Molecular Weight
735.57
References & Citations
[1]Choppin A, et al. Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model. Pharmacology. 2002 May;65 (2) :96-102.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NK1R

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