PROTAC FKBP Degrader-3

PROTAC FKBP Degrader-3

• CAS Number: 2079056-43-0
• UNSPSC Description: PROTAC FKBP Degrader-3 is a PROTAC that comprises a FKBP ligand binding group, a linker and an von Hippel-Lindau binding group. PROTAC FKBP Degrader-3 is a potent FKBP degrader[1].
• Target Antigen: FKBP; PROTACs
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-fkbp-degrader-3.html
• Smiles: CC[C@H](C(N1[C@H](C(O[C@H](CCC2=CC=C(OC)C(OC)=C2)C3=CC=CC(OCC(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4C[C@H](O)C[C@H]4C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)=O)=O)=O)=C3)=O)CCCC1)=O)C7=CC(OC)=C(OC)C(OC)=C7
• Molecular Weight: 1295.54
• References & Citations: [1]Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.
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