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TRPV antagonist 1

CAT: 0804-HY-U00330Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-U00330Size:1 Each
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Description
TRPV antagonist 1 is a transient receptor potential vanilloid (TRPV) antagonist, with an IC50 of < 250 nM.
CAS Number
1192871-27-4
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5H-Thiazolo[3,2-a]pyrimidin-5-one,_7-[_1E_-2-[2-_cyclopropylmethoxy_-3-methoxyphenyl]ethenyl]-6-[4-_trifluoromethoxy_phenyl]-.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C2=CC=C(OC(F)(F)F)C=C2)=C(/C=C/C3=CC=CC(OC)=C3OCC4CC4)N=C5N1C=CS5
Molecular Formula
C26H21F3N2O4S
Molecular Weight
514.52
References & Citations
[1]Reilly RM, et al. Analgesic potential of TRPV3 antagonists. Curr Top Med Chem. 2011;11 (17) :2210-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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