Products for Research Use Only
RegisterLogin

TRPC antagonist 1

CAT: 0804-HY-162090Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162090Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TRPC antagonist 1 (compound 15g) is a potent TRP channel (TRPC) antagonist with IC50s of 2.4 μM, 12.2 μM, 7.6 μM, 2.9 μM, and 3.4 μM for TRPC3, TRPC4, TRPC5, TPRC6, and TRPC7, respectively. TRPC antagonist 1 displays noteworthy anti-glioblastoma efficacy in vitro against U87 cell lines[1].
CAS Number
3027139-12-1
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trpc-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
NCCN(C1=NC(C(NC2=CC=C(O)C=C2)=O)=CS1)CC3=CC=C(C=CC=C4)C4=C3
Molecular Formula
C23H22N4O2S
Molecular Weight
418.51
References & Citations
[1]Shanshan Wang, et al. Discovery of N-alkyl-N-benzyl thiazoles as novel TRPC antagonists for the treatment of glioblastoma multiforme. European Journal of Medicinal Chemistry. 22 December 2023, 116066.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPC3; TRPC4; TRPC5; TRPC6; TRPC7

Related Products

CatalogName
HY-172600TRPC6 antagonist-1
HY-U00330TRPV antagonist 1
HY-170950P2Y14 antagonist 1
HY-170589-01GPR17 antagonist 1
HY-169849-01EphA2 antagonist 1
HY-130845-01AR antagonist 1
HY-162664-01STING antagonist-1
HY-U00320-01Neurokinin antagonist 1
HY-163701HA2AAR antagonist 1
HY-153258CaSR antagonist-1

Alternative Products

CatalogName
GTR19261550-01TRPC antagonist 1
GTR17967356TrpC Antibody
SF1159-5mgSKF96365 (TRPC inhibitor)
E110980Mouse TRPC ELISA Kit
P29287PCAMBIA1303-gpdA-EGFP-TrpC-Hygro
P54302PCAMBIA1303-gpdA-EGFP-TrpC-Bar
P0823PCAMBIA1303-TrpC-Hygro-gpdA-GFP
TBI1068-5MGSKF-96365, TRPC channel blocker
P21217PCAMBIA1303-gpdA-GFP-TrpC-Hygro
TBI2441-250MGPranlukast, Leukotriene CysLT1 antagonist; GPR17 antagonist

Popular Products