CGP-53153

• Description :

  CGP-53153 is a steroidal inhibitor of 5 alpha reductase with IC50s of 36 and 262 nM in rat and human prostatic tissue, respectively.

• UNSPSC :

  12352005

• Target :

  5 alpha Reductase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/CGP-53153.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]1([C@H]2C(NC(C)(C)C#N)=O)[C@](CC2)([H])[C@@](CC[C@](N3)([H])[C@@]4(C=CC3=O)C)([H])[C@]4([H])CC1

• Molecular Formula :

  C23H33N3O2

• Molecular Weight :

  383.53

• References & Citations :

  [1]H?usler A, et al. CGP-53153: a new potent inhibitor of 5alpha-reductase. J Steroid Biochem Mol Biol. 1996 Feb;57 (3-4) :187-95.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [149281-19-6]