CGP-20376

• Description :

  CGP-20376, a 5-methoxyl-6-dithiocarbamic-S- (2-carboxy-ethyl) ester derivative of Benzothiazole (HY-W012634), is an orally active and potent antifilarial drug. CGP-20376 has anthelmintic activity[1][2].

• UNSPSC :

  12352005

• Target :

  Parasite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/cgp-20376.html

• Smiles :

  O=C(O)CCSC(NC1=C(OC)C=C2N=C(C(C)(C)C)SC2=C1)=S

• Molecular Formula :

  C16H20N2O3S3

• Molecular Weight :

  384.54

• References & Citations :

  [1]J W Mak, et al. Antifilarial activity of CGP 20376 against subperiodic Brugia malayi in the leaf-monkey Presbytis cristata. Trop Med Parasitol. 1990 Mar;41 (1) :10-2.|[2]P Weber. Effects of the two new anthelmintic agents CGP 6140 and CGP 20376 on adult Paragonimus uterobilateralis in the experimental host Sigmodon hispidus. Trop Med Parasitol. 1987 Dec;38 (4) :335-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [81059-04-3]