CGP-75355

• Description :

  CGP-75355 is an inhibitor of HIV-1 protease with IC50 of 26 nM. CGP-75355 is a bis (L-tert-leucine) derivative[1][2].

• UNSPSC :

  12352005

• Target :

  HIV; HIV Protease

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Smiles :

  CC(C)(C)[C@@H](C(N[C@@H](CC1=CC=CC=C1)[C@@H](O)CN(NC([C@H](C(C)(C)C)NC(OC)=O)=O)CC2=CC=C(C3=CC=CC=C3)C=C2)=O)NC(OC)=O

• Molecular Formula :

  C39H53N5O7

• Molecular Weight :

  703.87

• References & Citations :

  [1]Bold, G., et al., (1998) . New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development. Journal of medicinal chemistry, 41 (18), 3387-3401.|[2]Wieslaw M. Kazmierski, (2011) . Antiviral Drugs: From Basic Discovery Through Clinical Trials.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [191594-64-6]